Dr Gay Crooks
Dr. Gay M. Crooks is Professor and Rebecca Smith Chair in the Departments of Pathology & Laboratory Medicine and Pediatrics in the David Geffen School of Medicine. She joined UCLA in 2009 and serves as Co-Director of the Broad Stem Cell Research Center and Director of the Cancer and Stem Cell biology Program of the Jonsson Comprehensive Cancer Center. She graduated in medicine at University of Western Australia and received her pediatric training at Princess Margaret Hospital in Perth and fellowship training in pediatric hematology-oncology at Children’s Hospital Los Angeles.
Dr. Crooks’s research program covers basic and translational studies of human hematopoiesis, a focus that is informed by her clinical role as a pediatric bone marrow transplant physician. The central theme of human hematopoiesis reaches into three related areas of interest for the laboratory: 1. The characterization and manipulation of human HSC and lymphoid progenitors in cord blood, bone marrow and thymus, 2. Mechanisms of growth and differentiation of the thymic micro-environment during the neonatal period, and 3. Hematopoiesis from human pluripotent stem cells. Her laboratory has recently developed a novel system to generate mature engineered T cells from human hematopoietic and pluripotent stem cells in vitro and is exploring the potential of using this platform technology for T cell immunotherapy.